⛸️ Invasive Carcinoma Of No Special Type

The most common histologic type of invasive breast cancer is now classified as invasive breast carcinoma of no special type (IBC-NST), changed in the fourth edition of the World Health Organization (WHO) Classification of tumors of the breast from invasive ductal carcinoma not otherwise specified (IDC-NOS). 1 The term “ductal” is no longer TRPS1 was highly expressed in 100% of triple-negative primary and metastatic invasive lobular carcinomas, 99% of triple-negative primary and metastatic invasive breast carcinoma of no special type (IBC-NST), and 95% of metaplastic breast carcinomas. In contrast, GATA3 and SOX10 were expressed in 94% and 0% of invasive lobular carcinomas, 63% Invasive lobular breast cancer (ILC) is the second most commonly diagnosed type of breast cancer in women, after invasive breast cancer of no special type (NST). ILC accounts for up to 15% of all invasive breast cancers in women. A lower frequency of axillary nodal metastasis in invasive lobular carcinoma than in invasive carcinoma of no special type has been reported in some series, the difference ranging from 3% to 10%. Distant Metastasis. Metastases of invasive lobular carcinoma differ from those of invasive carcinoma of no special type. Mixed ICC: prognosis poorer than pure but better than invasive ductal carcinoma of no special type (IDC, NST) Lymph node / distant metastasis is rare (BMC Cancer 2021;21:168) ICC: more favorable prognosis than invasive breast carcinoma with less cribriform pattern and low grade IDC (J Clin Exp Pathol 2013;6:445) Invasive carcinoma of no special type was the most common histological type in the study group (71.2%, 52/73). The luminal A and B subtypes were the major types of male breast carcinoma (60.9%, 34.8% respectively). Special type carcinomas should consist of at least 90% pure pattern. ___ No residual invasive carcinoma ___ Invasive carcinoma of no special type (ductal) ___ Micro-invasive carcinoma ___ Invasive lobular carcinoma ___ Invasive carcinoma with mixed ductal and lobular features Invasive ductal carcinoma of no special type - medullary pattern With the 5th Edition of the WHO Classification, medullary carcinoma ceased to be considered a distinct subtype of breast cancer 1JMU.

invasive carcinoma of no special type